Nutrients, Vol. 18, Pages 1185: Joint Associations of Accelerometer-Derived Intensity Gradient and Diet Quality with Frailty Among Rural Chinese Older Adults
Nutrients doi: 10.3390/nu18081185
Authors:
Ke Chen
Yating Liu
Ming Li
Meng Zhao
Kunli Wang
Ziwen Pan
Si Chen
Kefang Wang
Background/Objectives: Frailty is common among rural Chinese older adults despite relatively high daily physical activity, a phenomenon known as the “rural frailty paradox.” Conventional moderate-to-vigorous physical activity (MVPA) metrics rely on absolute cut-points and are often highly correlated with activity volume, limiting their ability to distinguish the roles of activity volume and activity intensity distribution. We therefore applied a cut-point-free accelerometer approach using average acceleration (AvAcc) and intensity gradient (IG) to distinguish activity volume from activity intensity distribution and to examine whether activity intensity distribution, together with diet quality, could help explain the rural frailty paradox beyond total activity volume alone. Methods: In this cross-sectional analysis of the Healthy Aging and Lifestyle Enhancement study, 1203 rural older adults were included. Physical activity (PA) was objectively measured using triaxial accelerometers to derive AvAcc and the IG. Diet quality was assessed using the China Prime Diet Quality Score (CPDQS), and frailty was assessed using the Fried frailty phenotype adapted for rural Chinese older adults. Multiple linear regression, joint effect models, and restricted cubic spline analyses were conducted after adjustment for age, sex, chronic disease status, total energy intake, and related covariates. Results: In mutually adjusted models, higher IG and CPDQS were independently associated with lower frailty scores, whereas AvAcc was not. In the fully adjusted model, IG (β = −0.14, p < 0.001) and CPDQS (β = −0.10, p < 0.001) were inversely associated with frailty score, while AvAcc showed no significant association (p = 0.665). In joint analyses, compared with the low-IG/low-CPDQS group, participants with high IG/high CPDQS had the lowest frailty scores (β = −0.28, p < 0.001), followed by those with low IG/high CPDQS (β = −0.20, p = 0.002). Restricted cubic spline analyses indicated a non-linear association between IG and frailty and an approximately linear inverse association for CPDQS. Conclusions: These findings suggest that, among rural older adults, frailty may be more strongly associated with activity intensity distribution than with total activity volume alone. Together with diet quality, this may help explain the rural frailty paradox.
Background/Objectives: Frailty is common among rural Chinese older adults despite relatively high daily physical activity, a phenomenon known as the “rural frailty paradox.” Conventional moderate-to-vigorous physical activity (MVPA) metrics rely on absolute cut-points and are often highly correlated with activity volume, limiting their ability to distinguish the roles of activity volume and activity intensity distribution. We therefore applied a cut-point-free accelerometer approach using average acceleration (AvAcc) and intensity gradient (IG) to distinguish activity volume from activity intensity distribution and to examine whether activity intensity distribution, together with diet quality, could help explain the rural frailty paradox beyond total activity volume alone. Methods: In this cross-sectional analysis of the Healthy Aging and Lifestyle Enhancement study, 1203 rural older adults were included. Physical activity (PA) was objectively measured using triaxial accelerometers to derive AvAcc and the IG. Diet quality was assessed using the China Prime Diet Quality Score (CPDQS), and frailty was assessed using the Fried frailty phenotype adapted for rural Chinese older adults. Multiple linear regression, joint effect models, and restricted cubic spline analyses were conducted after adjustment for age, sex, chronic disease status, total energy intake, and related covariates. Results: In mutually adjusted models, higher IG and CPDQS were independently associated with lower frailty scores, whereas AvAcc was not. In the fully adjusted model, IG (β = −0.14, p < 0.001) and CPDQS (β = −0.10, p < 0.001) were inversely associated with frailty score, while AvAcc showed no significant association (p = 0.665). In joint analyses, compared with the low-IG/low-CPDQS group, participants with high IG/high CPDQS had the lowest frailty scores (β = −0.28, p < 0.001), followed by those with low IG/high CPDQS (β = −0.20, p = 0.002). Restricted cubic spline analyses indicated a non-linear association between IG and frailty and an approximately linear inverse association for CPDQS. Conclusions: These findings suggest that, among rural older adults, frailty may be more strongly associated with activity intensity distribution than with total activity volume alone. Together with diet quality, this may help explain the rural frailty paradox. Read More