Nutrients, Vol. 17, Pages 2823: Association Between Anti-Inflammatory Diet, Dietary Diversity, and Depressive Symptoms Among Chinese Pregnant Women
Nutrients doi: 10.3390/nu17172823
Authors:
Binyan Zhang
Ke Men
Chao Li
Kun Xu
Baibing Mi
Jiaxin Cai
Leilei Pei
Shunming Zhang
Yonghong Ma
Ying Li
Shaonong Dang
Hong Yan
Background：Dietary inflammatory potential and dietary diversity during pregnancy may program depression, yet these associations remain poorly characterized. This study aimed to assess an anti-inflammatory diet and dietary diversity in relation to depressive symptoms. Methods：We analyzed data from 2244 pregnant women in the prospective longitudinal study. Depressive symptoms were defined as an Edinburgh Postnatal Depression Scale (EPDS) score ≥9.5. An anti-inflammatory diet was assessed using the reverse energy-adjusted Dietary Inflammatory Index (rEDII), derived from food frequency questionnaires. Dietary diversity was classified as either adequate or inadequate. Generalized estimating equations were performed. Results：Our findings demonstrated that a higher rEDII was associated with lower EPDS scores (β: −0.25; 95% CI: −0.37, −0.12) and a 13% reduction in the risk of depressive symptoms (RR: 0.87; 95% CI: 0.81, 0.93). Adequate dietary diversity was linked to a 22% lower risk of depressive symptoms (RR: 0.78; 95% CI: 0.64, 0.95). A significant interaction was observed between rEDII and dietary diversity in relation to depressive symptoms. Among women with inadequate dietary diversity, a higher rEDII was associated with a 15% reduction in depressive symptom risk (RR: 0.85; 95% CI: 0.80, 0.90). Conclusions：An anti-inflammatory diet was associated with a lower risk of depressive symptoms; this association was greater among women with inadequate dietary diversity.
Background：Dietary inflammatory potential and dietary diversity during pregnancy may program depression, yet these associations remain poorly characterized. This study aimed to assess an anti-inflammatory diet and dietary diversity in relation to depressive symptoms. Methods：We analyzed data from 2244 pregnant women in the prospective longitudinal study. Depressive symptoms were defined as an Edinburgh Postnatal Depression Scale (EPDS) score ≥9.5. An anti-inflammatory diet was assessed using the reverse energy-adjusted Dietary Inflammatory Index (rEDII), derived from food frequency questionnaires. Dietary diversity was classified as either adequate or inadequate. Generalized estimating equations were performed. Results：Our findings demonstrated that a higher rEDII was associated with lower EPDS scores (β: −0.25; 95% CI: −0.37, −0.12) and a 13% reduction in the risk of depressive symptoms (RR: 0.87; 95% CI: 0.81, 0.93). Adequate dietary diversity was linked to a 22% lower risk of depressive symptoms (RR: 0.78; 95% CI: 0.64, 0.95). A significant interaction was observed between rEDII and dietary diversity in relation to depressive symptoms. Among women with inadequate dietary diversity, a higher rEDII was associated with a 15% reduction in depressive symptom risk (RR: 0.85; 95% CI: 0.80, 0.90). Conclusions：An anti-inflammatory diet was associated with a lower risk of depressive symptoms; this association was greater among women with inadequate dietary diversity. Read More