This prospective study among pregnant slum-dwelling Indian women highlights the need to address both pre-pregnancy BMI and regular weight monitoring throughout pregnancy to enhance the likelihood of favourable neonatal outcomes.
ABSTRACT
The influence of early pregnancy weight and gestational weight gain (GWG) on neonatal outcomes among Indian slum-dwellers remains understudied. A prospective cohort study summarised maternal weight trajectories using the longitudinal clustering technique and explored associations between these clusters and neonatal outcomes (low birthweight, small for gestational age [SGA] and preterm births) among 423 pregnant slum-dwelling women in Pune, India. Sociodemographic data, height and weight were measured at enrolment (< 12 weeks, ‘early pregnancy’). Weight was additionally measured at 23 ± 1 (‘mid-pregnancy’), 33 ± 1 (‘late pregnancy’), 36–37 and 39–40 weeks. The mean age was 24.7 (95% CI, 23.3, 25.1) years and the mean BMI at enrolment was 22.3 (95% CI, 21.9, 22.7) kg/m2. Underweight women had the highest GWG rates and total GWG, while obese women had the lowest. Four clusters were identified: Cluster 1 (n = 124, 97% normal and overweight women, GWG rate: 0.27 (95% CI, 0.24, 0.30) kg/week early-late pregnancy) was the reference group. Women in Cluster 2 (n = 146, 93% underweight and normal weight women, GWG rate: 0.31 (95% CI, 0.28, 0.34) kg/week early-late pregnancy) had a higher risk of having SGA and preterm newborns and women in Cluster 3 (n = 68, 100% overweight and obese women, GWG rate: 0.17, 95% CI, 0.12, 0.22 kg/week early-late pregnancy) had a higher risk of having preterm newborns than Cluster 1. The women in Cluster 4 (n = 85, 100% underweight and normal weight, mean early-late pregnancy GWG rate of 0.47, 95% CI, 0.44, 0.50 kg/week) showed no higher risk of adverse neonatal outcomes. This study highlights the need to monitor both pre-pregnancy BMI and weight throughout pregnancy to enhance the possibility of favourable neonatal outcomes.
Maternal &Child Nutrition, EarlyView. Read More