Nutrients, Vol. 17, Pages 2913: Caffeinated Energy Drink Formulations Differentially Impact Hydration Versus Water: Does Habitual Caffeine Intake or Biological Sex Matter?

Nutrients, Vol. 17, Pages 2913: Caffeinated Energy Drink Formulations Differentially Impact Hydration Versus Water: Does Habitual Caffeine Intake or Biological Sex Matter?

Nutrients doi: 10.3390/nu17182913

Authors:
Melinda Millard-Stafford
Brian Hack
Alec Harp
Ella Smith

Background/Objectives: The beverage hydration index (BHI) assesses the relative hydration properties of beverages. Commercially available caffeinated energy drinks (with and without electrolytes or carbohydrates) were compared to water. Methods: Fourteen men and fourteen women completed four trials: 500 mL water plus either 500 mL water or caffeinated energy drink beverage (CAF) with 280 mg, CAF (280 mg) plus electrolytes (CAF + E), or CAF (106 mg) + E and carbohydrates (CAF + CE). Participants’ habitual caffeine intake (0–535 mg/day) was used to stratify users into naïve (<25 mg/day, n = 19) or regular users. Results: BHIs at 240 min for CAF (0.86 ± 0.16) and CAF + E (0.91 ± 0.16) were lower (p < 0.001) versus water (1.0 ± 0.0) and CAF + CE (1.01 ± 0.12). Urine mass with CAF and CAF + E was significantly greater (p < 0.01) by 244 g and 162 g versus CAF + CE. The % fluid retained at 240 min was lower (p < 0.001) for CAF (−71.2 ± 21.5%) and CAF + E (−65.1 ± 26.3%) versus CAF + CE (−46.4 ± 18.8%). Habitual intake status had no effect on the BHI (p = 0.827) between the naïve (0.92 ± 0.1) and habitual user group (0.93 ± 0.1) averaged across all three caffeinated beverages for 120 and 240 min. At 240 min, the drink (p < 0.001) and drink x sex interaction (p = 0.042) indicated women had higher BHI than men (p = 0.03) for caffeinated drinks despite higher relative fluid and caffeine dosages. Conclusions: A low-carbohydrate–electrolyte beverage with moderate caffeine had similar hydration properties compared to water; however, this differs from beverages with higher caffeine containing limited carbohydrate and/or electrolytes, which were inferior to water. Habitual caffeine intake had no apparent influence, but men and women exhibited differences in the diuretic response to energy drink consumption.

​Background/Objectives: The beverage hydration index (BHI) assesses the relative hydration properties of beverages. Commercially available caffeinated energy drinks (with and without electrolytes or carbohydrates) were compared to water. Methods: Fourteen men and fourteen women completed four trials: 500 mL water plus either 500 mL water or caffeinated energy drink beverage (CAF) with 280 mg, CAF (280 mg) plus electrolytes (CAF + E), or CAF (106 mg) + E and carbohydrates (CAF + CE). Participants’ habitual caffeine intake (0–535 mg/day) was used to stratify users into naïve (<25 mg/day, n = 19) or regular users. Results: BHIs at 240 min for CAF (0.86 ± 0.16) and CAF + E (0.91 ± 0.16) were lower (p < 0.001) versus water (1.0 ± 0.0) and CAF + CE (1.01 ± 0.12). Urine mass with CAF and CAF + E was significantly greater (p < 0.01) by 244 g and 162 g versus CAF + CE. The % fluid retained at 240 min was lower (p < 0.001) for CAF (−71.2 ± 21.5%) and CAF + E (−65.1 ± 26.3%) versus CAF + CE (−46.4 ± 18.8%). Habitual intake status had no effect on the BHI (p = 0.827) between the naïve (0.92 ± 0.1) and habitual user group (0.93 ± 0.1) averaged across all three caffeinated beverages for 120 and 240 min. At 240 min, the drink (p < 0.001) and drink x sex interaction (p = 0.042) indicated women had higher BHI than men (p = 0.03) for caffeinated drinks despite higher relative fluid and caffeine dosages. Conclusions: A low-carbohydrate–electrolyte beverage with moderate caffeine had similar hydration properties compared to water; however, this differs from beverages with higher caffeine containing limited carbohydrate and/or electrolytes, which were inferior to water. Habitual caffeine intake had no apparent influence, but men and women exhibited differences in the diuretic response to energy drink consumption. Read More

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