Nutrients, Vol. 17, Pages 3700: Nutritional Modulation of the Gut Microbiome in Relation to Prenatal Lead-Induced Neurotoxicity: A Review
Nutrients doi: 10.3390/nu17233700
Authors:
Shoshannah Eggers
Kiran P. Nagdeo
Kshitij Sachdev
Delaney Robinson
Andrea L. Deierlein
Jamil M. Lane
Chris Gennings
Ryan W. Walker
Linda Snetselaar
Nichole Nidey
Elizabeth E. O’Neal
Vishal Midya
Prenatal exposure to lead (Pb) is a well-established risk factor for adverse neurodevelopmental outcomes. Despite its recognized risks, prenatal Pb exposure remains largely unregulated and poorly addressed in public health policy. Evidence suggests that the gut microbiome may mediate the neurotoxic effects of metals, offering a potential target for intervention. Here we discuss how nutritional factors, particularly those influencing the gut microbiome, may reduce the neurotoxicity of prenatal Pb exposure.
Prenatal exposure to lead (Pb) is a well-established risk factor for adverse neurodevelopmental outcomes. Despite its recognized risks, prenatal Pb exposure remains largely unregulated and poorly addressed in public health policy. Evidence suggests that the gut microbiome may mediate the neurotoxic effects of metals, offering a potential target for intervention. Here we discuss how nutritional factors, particularly those influencing the gut microbiome, may reduce the neurotoxicity of prenatal Pb exposure. Read More