ABSTRACT
Background
Coeliac disease is an autoimmune disorder resulting from the consumption of gluten in genetically susceptible individuals. Current treatment is a lifelong gluten-free diet that significantly affects quality of life. Food-related quality of life (FRQoL) refers to the impact of food, nutrition, eating and drinking on the psychosocial aspects of life. The aim of this study was to examine FRQoL in patients with coeliac disease.
Methods
Patients with confirmed coeliac disease completed the validated FR-QoL-29 questionnaire adapted for coeliac disease (FR-QoL-29-Coeliac) and provided demographic and clinical information.
Results
Questionnaires were completed by 138 adults (62% female, mean age 52.3 SD ± 18.6). FR-QoL-29 scores were mean 85.8 (SD ± 23.1). The lowest FR-QoL-29 scores were in the 18–35 year age group (76.6 ± 17.2) compared with the highest in the 56+ age group (92.5 ± 22.3, p = 0.002). Patients with ≥ 4 gastrointestinal (GiS) symptoms had significantly lower FR-QoL-29 scores (77.9 ± 20.7) compared with those with 1–3 GiS (96.7 ± 21, p = 0.0001).
Conclusions
FRQoL is impaired in coeliac disease and is particularly lower in younger people and those with greater GI symptom burden. Further research should examine the mechanisms that reduce FRQoL in coeliac disease to identify interventions that minimise the burden for patients.
Journal of Human Nutrition and Dietetics, Volume 38, Issue 3, June 2025. Read More